Peter Herman, PhD

Associate Research Scientist of Diagnostic Radiology

Contact

Address:
Yale University, School of Medicine
Magnetic Resonance Research Center
TAC, N144, 300 Cedar Street
New Haven, Connecticut 06520-8043
United States

Email: peter.herman@yale.edu
Telephone: (203) 785-6170
Fax: (203) 785-6643

Education

Semmelweis University of Medicine, Budapest, Hungary
MD 1994
Medicine

Semmelweis University, Budapest, Hungary
PhD 2002
Physiology

Yale University, New Haven, CT
Postdoctoral Training 2003-2005
Magnetic Resonance and Electrophysiology

Please click here for Curriculum Vitae

Research Interests

My research interest revolved around the characterization of cerebral blood flow. We started to use the fractal and chaotic paradigms to describe the blood flow fluctuations in different physiological states, mainly in experimental animals. Additional to the optical methods, I studied the functional MRI techniques and microelectrical neural recordings to describe the effect of small perturbations to the cerebral blood flow. I am interested in the resting state fluctuations of physiological signals in the brain and in the understanding of the neurovascular coupling. I am working with different experimental and modeling methods to describe the blood flow, oxygen supply, and energetics during functional neuronal activation.

Selected Publications

1. Sanganahalli BG, Herman P, Hyder F.(2008) Frequency-dependent tactile responses in rat brain measured by functional MRI. NMR Biomed. 21(4):410-416.
2. Maandag NJ, Coman D, Sanganahalli BG, Herman P, Smith AJ, Blumenfeld H, Shulman RG, Hyder F.(2007) Energetics of neuronal signaling and fMRI activity. Proc Natl Acad Sci U S A. 104(51):20546-20551.
3. Kocsis L, Herman P, Eke A. (2006) Mathematical model for the estimation of hemodynamic and oxygenation variables by tissue spectroscopy. J Theor Biol. 241(2):262-275.
4. Herman P, Eke A. (2006) Nonlinear analysis of blood cell flux fluctuations in the rat brain cortex during stepwise hypotension challenge. J Cereb Blood Flow Metab. 26(9):1189-1197.
5. Eke A, Herman P, Hajnal M. (2006) Fractal and noisy CBV dynamics in humans: influence of age and gender. J Cereb Blood Flow Metab. 26(7):891-898.
6. Herman P, Trubel HK, Hyder F. (2006) A multiparametric assessment of oxygen efflux from the brain.J Cereb Blood Flow Metab. 26:79-91.
7. Trubel H, Herman P, Kampmann C, Huth R, Maciejewski PK, Novotny E, Hyder F. (2004) A novel approach for selective brain cooling: implications for hypercapnia and seizure activity. Intensive Care Med 30:1829-1833.
8. Eke, A., Herman, P., Kocsis L., Kozak L.R. (2002) Fractal characterization of complexity in temporal physiological signals. Physiol. Meas. 23:R1-R38.
9. Herman, P., L. Kocsis, A. Eke (2001) Fractal branching pattern in the pial vasculature in the cat. J. Cereb. Blood Flow and Metabol., 21:741-754.
10. Eke, A., P. Herman, J.B. Bassingthwaighte, G.M. Raymond, D.B. Percival, M. Cannon, I. Balla, and C. Ikrenyi. (2000) Physiological time series: distinguishing fractal noises from motions. Pflugers Arch. - Eur. J. Physiol., 439: 403-415.

For a further list of Herman's publications, please see PubMed.